Hi Pavan,
Attached sheet does list out information as required. Please note, in order to create relationship amongst data set you always have to data which are many to one kind of relationship. When I saw many I mean the data set which are transactional and one which is unique then you can create relationships (pretty much like in Access)
In the attached sheet I have created 3 new data set for the one type data set (unique values) which are customer data, Product data and PO#. Then load them as data model and then plot the pivot.
To your question on to include calculated column not sure what is the desired output you want to have based on which we can have either a measure or a calculated column.
Hope this helps.
Kind regards,
A!